The Robinas, a Detroit couple in their eighties have been married for nearly 60 years. Ella has terminal cancer and John has been suffering from Alzheimer’s for several years. Even though their doctors and middle-aged children are against Ella's decision to refuse medical treatment, she decides that she and John should have one last hoorah. They get into their old RV and head west to Disneyland taking historic Route 66. Their story is sad, funny, romantic, and deeply moving.